Viagra firm to begin offering ‘budget’ Ozempic costing $50 per week

Telehealth giant Hims will soon sell its own version of Ozempic that costs just a quarter of the price of the name brand.

Hims, a wellness start-up known for its hair and sex supplements, announced Monday that it will sell a ‘copycat’ of semaglutide, the active ingredient in Ozempic and Wegovy.  

This is known as compounding, which is when companies can offer prescription drugs without FDA approval to combat shortages. 

The injection cost will start as just $199 for a month’s supply, whereas Ozempic and Wegovy can total over $1,300. This price also includes unlimited consultations with a doctor. 

Hims did not announce when the drug will be available. 

Supplement giant Hims will sell its own version of semaglutide, the active ingredient in Ozempic and vinix 지속시간 Wegovy, for just $199 per month

Hims also specializes in sexual health, hair loss, and mental health supplements and medications

Hims said the goal is to help customers get access to the drugs without ‘navigating the shortages and costs that are currently limiting access to the branded medications.’ 

The news comes as several types of drugs, including Ozempic and Wegovy face record-high shortages. 

A recent report from the American Society of Health-System Pharmacists (ASHP) and the University of Utah Drug Information Service, for example, found that 323 drugs are currently running low, surpassing 2014’s high of 320.

Andrew Dundum, Hims chief executive officer, said: ‘It’s going to be a huge part of the weight loss category moving forward.

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‘Our belief is that compounding can be done very safely, if done correctly.’ 

The announcement comes after Hims launched a weight loss program in December, which includes access to oral, non-GLP-1 medications. 

Compounded weight loss drugs have become more popular in recent months as Ozempic maker Novo Nordisk and Wegovy manufacturer Eli Lilly have struggled to meet surging demand for 비닉스100mg복용법 the injections. 

Though the FDA allows companies to make compounded drugs like these, the agency does not review their safety or efficacy.

Mr Dundum did not say where the new drugs will be made but noted it is ‘one of the largest generics manufacturers.’  

Hims also announced that it will offer compounded versions of tirzepatide, the active ingredient in Mounjaro and Zepbound, in the coming months. 

The company also said it will offer name-brand Ozempic and Wevovy once there is enough supply. 

FDA

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Lower Back Pain: Causes, Treatment, and Prevention

Low back pain- The most common causes of lower back painLower back pain is a common ailment that affects millions of people worldwide. It can range from mild discomfort to debilitating pain, significantly impacting daily activities. Understanding the causes and effective treatment options can help individuals manage this condition and improve their quality of life.  

Causes of Lower Back Pain

Lower back pain can result from various factors, including:

Muscle Strain: Overexertion, poor posture, or lifting heavy objects improperly can strain the muscles and ligaments in the lower back.

Herniated Disc: A herniated disc occurs when the soft, gel-like center of a spinal disc bulges or ruptures, putting pressure on the nerves.

Arthritis: Osteoarthritis, a degenerative joint disease, can cause inflammation and pain in the lower back.

Spinal Stenosis: lower back pain causes and Treatment This condition occurs when the spinal canal narrows, compressing the nerves.

Scoliosis: A curvature of the spine can misalign the bones and muscles, leading to lower back pain causes and treatment back pain.

Stress: Emotional stress can contribute to muscle tension and pain in the lower back.

Treatment for Lower Back Pain

The appropriate treatment for lower back pain depends on the underlying cause and severity of the condition. Common treatment options include:

Rest and Ice: Resting the affected area and applying ice can help reduce inflammation and pain.

Over-the-Counter Pain Relief: Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen can alleviate pain and inflammation.

Physical Therapy: A physical therapist can teach exercises and stretches to strengthen the back muscles, improve posture, and reduce pain.

Chiropractic Care: Chiropractors can manipulate the spine to improve alignment and reduce pain.

Massage Therapy: Massage can help relax muscles and reduce tension in the lower back.

Corticosteroid Injections: In severe cases, corticosteroid injections can be used to reduce inflammation and pain.

Surgery: In rare cases, surgery may be necessary to address underlying conditions such as herniated discs or spinal stenosis.

Preventing Lower Back Pain

While it may not always be possible to prevent lower back pain, adopting healthy habits can significantly reduce the risk:

Maintain Good Posture: Pay attention to your posture while sitting, standing, and lifting objects.

Exercise Regularly: Strengthen your core muscles and improve flexibility through regular exercise.

Lift Properly: Bend your knees, not your back, when lifting heavy objects.

Manage Stress: Practice stress-reduction techniques like meditation or yoga.

Maintain a Healthy Weight: Excess weight can put strain on the lower back.

Ergonomic Workspace: Ensure your workplace is ergonomically designed to support good posture.

Lower back pain is a common problem that can significantly impact quality of life. By understanding the causes and effective treatment options, individuals can manage this condition and reduce its symptoms. Prevention strategies, such as maintaining good posture, exercising regularly, and managing stress, can also help minimize the risk of developing lower back pain. If you are experiencing persistent lower back pain, consult with a healthcare professional for a proper diagnosis and treatment plan.

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Ядовитый дурман – этто материала, воздействующие сверху психику да физическое фрустрация лица, погружающие к связи и еще разбитию личности. Сегодня есть различные виды наркотиков, всяк изо тот или другой показывает погибельное трансвлияние на здоровье. Разберёмся, яко именно ядовитый дурман разламывают эндосимбионт равным образом тот или другой группы субстанций сугубо опасны.

1. Опioиды

КО опиоидам относят таковые наркотики, яко опиоид, снотворное, Героин кодеин а также другие производные опийного мака. Сии материалы изъявляют сильное суггестивность на центральную лихорадочную государственное устройство, провоцируя эйфорию также подавляя болевые ощущения. Однако при постоянном потреблении созревает здоровущая физическая зависимость. Урон опиоидов состоит в течение стремительном разрушении внутренних органов, начиная сердце, почки и еще печень. Утилизация героина через слово приводит для передозировкам, возбуждающим приостановку дыхания равным образом смерть.

2. Амфетамины и стимуляторы

БУКВА этой группе смотрятся такие наркотики, как эфедрин, Героин метамфетамин (хрусталь) а также кокаин. Настоящие вещества разгонят опус центральной нервическою организации, вызывая яроводье энергии и улучшение настроения. Однако долгое употребление приводит к истощению организма, созреванию паранойи, галлюцинаций и психозов. Амфетамины истощают запасы серотонина равным образом дофамина в течение мозге, вызывая депрессию и необратимые изменения на психике. Сверх того, данные материалы уничтожающе воздействуют на штаб-квартира, увеличивая риск инфарктов и инсультов.

3. Каннабиоиды

Превалирующим наркотиком этой категории представляется марихуана. Хотя почти многие мыслят её менее вредной, нежели другие материи, постоянное курение марихуаны что ль звать хронические заболевания лёгких а также психические расстройства. Каннабиоиды оказывают большое влияние сверху координацию течений и когнитивные функции, ухудшая эйдетизм а также способность буква обучению. Продолжительное утилизация марихуаны что ль привести ко амотивационному синдрому – состоянию, при каком явантроп теряет интерес ко бытие (а) также деятельности.

4. Галлюциногены

Галлюциногены, эти яко НАРКОТИК, наркотик (микромицеты) и психоделика, поднимают изменённое цветовосприятие самом деле, инициируя броские галлюцинации. Хотя бы физиологическая зависимость от этих наркотиков раскручивается эпизодично, ихний употребление может послужить причиной гнетущие психические расстройства, этакие как шизуха и длительные депрессивные эпизоды. Потеря галлюциногенов объединен капля риском “плохих трипов”, эпизодически человек чувствует густые опасения а также паранойю, коие могут сопровождаться невольными атаками.

5. Депрессанты

Сюда входят материалу, такие как барбитураты, бензодиазепины а также ГБЛ (лактон). Сии наркотики быть хозяином успокаивающим действием, снижая ярус тревожности (а) также расслабляя организм. Однако город смогут заключаться экстренно опасны при передозировке, так яко ярко тормозят чухалка и чуткий ритм. Филиация от депрессантов развивается быстро, приводя к состояниям постоянной апатии, сонливости а также дезориентации.

6. Искусственные наркотики

Эта царство подсоединяет в течение себе чертова гибель субстанций, этих как экстази (MDMA), “спайсы” и “соли чтобы ванн” (искусственные катеноны). Данные ядовитый дурман смогут показывать разнородное суггестивность на эндосимбионт – через стимуляции ут психодислептического эффекта. Утрата синтетических наркотиков содержится в течение их непонятном составе, яко как через слово они охватывают хим материала, которые бессчетно подверглись достаточному исследованию. Это повышает рискованность серьёзных кишечных инфекциях, дефектов внутренних организаций равным образом психологических расстройств.

Тонкопсихологический а также соц вред

Сверх прямого вреда для здоровья, наркотики рушат человек а также соц связи. Явантроп, зависимый через наркотиков, постепенно лишается экспрессконтроль над своей жизнью, сосредотачиваясь исключительно на отыскивании свежих доз. Это приводит буква разбитию связей с семьей и корешками, Героин утрате опуса равно социальной изоляции. Психические итоги подсоединяют в себе развитие депрессии, беспокойных расстройств также суицидальных мыслей.

Заключение

Ядовитый дурман – это этап к полному разламыванию организма (а) также личности. Любая группка наркотических веществ изъявляет свой в доску воздействие, но финал хронически одинаков – утрата здоровья, разрушенные отношения да потеря значения жизни. Борьба с наркотической подчиненностью требует единого подхода, заключающего медицинское лечение также психическую шефство, но самое главное – осознанное решение отказаться через сего безудержного пути.

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Rock Breaker a hundred and one

How do hydraulic rock breakers work? Rock breakers perform primarily based on the precept of applied pressure. The machine applies strain to a small piston within the rock. This giant amount of stress in a small area breaks generates drive throughout the onerous slab, breaking it comparatively effectively. The weight of the rock breaker head determines the magnitude of the applied force. Both types have mostly the identical components. The hydraulic breaker encompasses a various range of variations, with two notable types prominently acknowledged: the internal valve kind and the outer valve type. Inside this classification, the Soosan breaker stands as a remarkable instance of the internal valve type, while the Furukawa breaker represents the outer valve type. Although they fall below completely different categories, it is value noting that both sorts share a major resemblance when it comes to their constituent components. These elements, which kind the core of their functioning, exhibit putting similarities between the 2 breaker varieties, highlighting their widespread underlying design principles and operational mechanisms. The handrails comply with ISO 2867:2011 necessities. Make service work simpler and safer with optionally available inspection lighting. With the flip of a change, lights will illuminate the engine, FRR090 pump, battery, and radiator compartments to reinforce visibility. Improve jobsite safety. Add a swing alarm to alert people when you’re rotating from trench to stockpile and again again.

It’s greatest to ask your gear supplier about one of the best method to lubricate breakers in your working conditions. Many makers suggest pumping grease into the breaker bushing till you see grease exiting the underside of the bushing. It ensures the void between the bushings and the software steel is filled and displaces outdated grease new. Grease more usually in dry, dusty environments, if the instrument appears to be like dry, drags in the bushing or shiny put on spots are rubbed on its shank. Modern considering, superior efficiency, the benchmark in technology for Hydraulic Breakers. Whether you’re demolishing city buildings, excavating street tunnels, eradicating slag from blast furnaces, or performing highway maintenance, Indeco North America has a hammer to fit your specific carrier, application, and funds! Featuring fuel-saving know-how, the unique Intelligent Hydraulic System and obtainable in 21 heavy-responsibility models in power lessons ranging from 200 ft.

The Sandvik BR777i is dependable and durable with long wear times on all elements. Membrane-kind accumulator assists with power shops while defending towards hydraulic spikes. This permits fixed high productivity whereas maintaining stability and security. Subject replaceable instrument bushing and a low-maintenance design ensure optimum breaker uptime, and the fact that each one components are readily out there ensures they’re straightforward to substitute. The BR777i is extremely environment friendly with low operating prices.

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Diabetic Foot Pain: A Guide to Prevention and Treatment

Creative Help design help illustration illustrator peanuts the creative pain vectorDiabetic foot pain is a serious complication that can lead to ulcers, infections, and even amputation if not addressed promptly. It occurs due to nerve damage (neuropathy) and poor blood circulation (ischemia) in the feet, which can make it difficult to detect minor cuts, blisters, or other injuries.

Understanding Diabetic Foot Pain

Diabetic foot pain is often characterized by:

Numbness or tingling in the feet

Burning or stabbing pain

Sensitivity to touch

Poor wound healing

Sores or ulcers that don’t heal

Prevention is Key

Preventing diabetic foot pain involves regular foot care and monitoring. Here are some essential steps:

Daily inspections: Examine your feet daily for any signs of redness, swelling, blisters, or cuts.

Proper footwear: Wear well-fitting shoes that provide adequate support and cushioning. Avoid tight-fitting shoes or going barefoot.

Foot care: Keep your feet clean and foot pain treatment dry. Trim your toenails straight across to prevent ingrown toenails. Avoid soaking your feet for extended periods.

Regular check-ups: See your doctor for regular foot exams to assess your risk for foot complications.

Treatment Options

If you experience diabetic foot Pain Treatment pain, it’s crucial to seek medical attention immediately. Treatment may involve:

Wound care: If you have a sore or ulcer, your doctor will clean and dress it to prevent infection.

Offloading: Special shoes or devices can help relieve pressure on affected areas of your foot.

Medication: Medications may be prescribed to manage pain, prevent infection, or improve blood circulation.

Surgery: In severe cases, surgery may be necessary to treat infections, correct deformities, or improve blood flow.

Diabetic foot pain is a serious condition that can have devastating consequences. By practicing good foot care, monitoring your feet regularly, and seeking prompt medical attention, you can significantly reduce your risk of developing foot complications. If you have diabetes, make foot care a priority to maintain your overall health and well-being.

The History of Computers: A Journey Through Time and Scientific Developments

The evolution of computers is a fascinating story of human ingenuity and scientific advancement. From ancient counting tools to today’s powerful supercomputers, the journey of computing technology spans thousands of years, touching multiple fields such as mathematics, engineering, and computer science. This blog will explore the milestones of computing history and the significant scientific breakthroughs that have shaped modern computers.

Black History Month black details digital illustrations february graphic graphic design history illustration month texture typography1. Early Mechanical Computers: The Foundations

The history of computing dates back to the ancient world when humans first invented tools to aid calculations. Early examples include the abacus, used by the Mesopotamians and later adopted by civilizations like the Greeks and Romans. This basic counting tool is the earliest known mechanical device used to aid in arithmetic processes.

In the 17th century, scientific and technological advances took a major leap with the invention of mechanical calculators. The Pascaline, invented by Blaise Pascal in 1642, and the Stepped Reckoner by Gottfried Wilhelm Leibniz were two early mechanical devices designed to perform basic arithmetic. Though these machines were limited in their functionality, they paved the way for the first programmable devices.

2. Charles Babbage and the Analytical Engine: The Birth of Modern Computing

The journey toward modern computers took a monumental leap in the 19th century, thanks to Charles Babbage. Often referred to as the “father of the computer,” Babbage conceptualized the Analytical Engine in the 1830s, which is considered the first design of a general-purpose computer. This machine could be programmed to perform different tasks, a concept that underpins modern computers.

Babbage’s machine was never completed in his lifetime, but his pioneering work laid the foundation for the next wave of computing breakthroughs. His collaborator, Ada Lovelace, is also credited with being the first computer programmer, as she wrote the first algorithm intended for Babbage’s machine. Her work highlighted the potential of computers beyond simple number-crunching, introducing the idea that machines could process symbolic data.

3. The Advent of Electromechanical Computers

The 20th century marked the transition from mechanical to electromechanical computing. In 1936, Alan Turing, a British mathematician, introduced the concept of the Turing Machine, an abstract mathematical model that could simulate any algorithm. The Turing Machine laid the theoretical groundwork for computing and has since become a central concept in the study of computer science.

During World War II, the need for code-breaking and other wartime computations led to the development of several groundbreaking machines. The Harvard Mark I, built by Howard Aiken in 1944, and the Colossus, a British code-breaking machine, were early examples of electromechanical computers. These machines used a combination of relays and vacuum tubes to perform calculations more rapidly than any mechanical device.

4. The Invention of the Electronic Computer: ENIAC and Beyond

The post-war period saw the birth of fully electronic computers. The Electronic Numerical Integrator and Computer (ENIAC), developed by John Presper Eckert and John Mauchly at the University of Pennsylvania in 1945, was one of the first general-purpose electronic computers. ENIAC used thousands of vacuum tubes to perform high-speed calculations and was hailed as a marvel of modern engineering.

The development of the stored-program architecture in 1945 by John von Neumann marked another critical milestone. Known as the von Neumann architecture, it is the foundation of most modern computers. This architecture allowed computers to store both data and programs in memory, making them much more versatile and capable of handling a wide range of tasks.

5. The Era of Transistors and Microprocessors: The Rise of Personal Computing

The invention of the transistor in 1947 by John Bardeen, Walter Brattain, and William Shockley at Bell Labs revolutionized computing. Transistors replaced vacuum tubes, making computers smaller, faster, and more energy-efficient. This development eventually led to the creation of the first commercially available computers, such as the UNIVAC I, which was used for business and government applications in the early 1950s.

In the 1970s, the invention of the microprocessor—a single chip containing a computer’s processing unit—ushered in the era of personal computing. The Intel 4004, developed in 1971, was the world’s first commercially available microprocessor. By integrating multiple functions into a small chip, the microprocessor enabled the creation of smaller, more affordable computers. Companies like Apple, IBM, and Microsoft became pioneers in the personal computer revolution, with machines like the Apple II, IBM PC, and the rise of operating systems like MS-DOS and Windows.

6. The Modern Age: Supercomputing, AI, and Quantum Computing

Today, computers are faster, more powerful, and more compact than ever before. Advances in technology have led to the creation of supercomputers, capable of performing trillions of calculations per second. These machines are used in fields like climate modeling, space exploration, and complex simulations in physics and biology.

The rise of artificial intelligence (AI) has also transformed the landscape of computing. With advancements in machine learning and neural networks, computers can now perform tasks that require human-like intelligence, such as image recognition, natural language processing, and playing strategic games. AI-powered systems like IBM’s Watson and Google’s DeepMind demonstrate the potential of computers to revolutionize industries ranging from healthcare to finance.

Looking further into the future, quantum computing is an emerging field that could drastically change the way we think about computation. Quantum computers, which leverage the principles of quantum mechanics, have the potential to solve problems that are currently intractable for classical computers. Though still in its early stages, quantum computing holds promise for breakthroughs in cryptography, drug discovery, and materials science.

Conclusion

The history of computers is a testament to the power of human creativity and the ongoing quest for knowledge. From the simple abacus to the cutting-edge quantum computer, each step in the evolution of computing has been driven by scientific innovation. As we look toward the future, the potential of computers to transform the world seems limitless, fueled by advancements in AI, quantum computing, and beyond. The journey is far from over, and the next great breakthrough may be just around the corner.

What is A Tachograph?

Why do I need a tachograph? The need to log driver exercise was first introduced in 1969 for social and road security reasons. These reasons haven’t modified. Because the government’s well-known Assume fatigue marketing campaign states – tiredness kills. A tachograph allows businesses to analyse precise driver hours and distance travelled against the drivers’ hours guidelines put in place by UK, EU, and AETR. The Automobile and Operator Services Company is scorching on handing out penalties for any authorized infringements, including not having a tachograph put in. So the largest purpose why you need a tachograph is solely – it’s the legislation! Usually there isn’t much distinction in utilizing a digital tachograph card for the first time and at a later stage. How to vary the language settings on a digital tachograph? The language of the tachograph might be changed by urgent the main or Okay button of the digital tachograph, then use the arrow buttons to choose ‘settings’. From there you’ll be able to select a language and set the language and affirm. Word: тахограф москва Watch out to not set the flawed language as it becomes tougher to undergo the menu and set it back. The Distant Tacho Obtain solution from FleetGO enables the studying obligation for a whole fleet to be fulfilled automatically.

In short, digital tachograph administration software turns the digital tachograph into a robust management device for fleets, delivering so far more value than compliance alone. Geotab’s Digital Tachograph solution assists with compliance with European Union (EU) drivers’ hours guidelines. Moreover, options supplied by select Geotab Market partners assist compliance with native working time guidelines as enforced by regional authorities. Geotab’s distant tachograph obtain resolution makes administration and compliance with drivers’ hours rules and tachograph rules painless. The software program affords driver identification, actual-time tacho standing, remote download and analysis, and way more, all accessed by the powerful MyGeotab fleet management platform.

“What are tachograph laws? What are tacho breaks? These are simply among the Google search terms used around tacho and tachographs. It exhibits that while HAU drivers and hauliers could effectively be conversant in the broad tachograph legislation, there are many nuances and country differentiations to think about. Picture via Google Developments, worldwide search for “Tachograph” over 12 months. What is an Octane Number? What is an Odometer? What’s an Oil Cooler? What’s an Oil Filter? What’s an On-Street Price? What is an On-Street Value? What is an Possibility Pack? What is an RPM? A tachograph is a system which is able to document a vehicle’s distance, time log, average pace and other related journey info. The straightforward mechanical tachograph writes on a round piece of paper which consistently turns all through the work day (a bit just like the quaint seismograph). The marker strikes nearer to or farther from the centre in line with the driving pace.

Data have to be stored for 2 weeks after the tip of each designated period. Read extra on Tachograph Guidelines: What European drivers and Hauliers Need to Know. Visit our Tachograph Management web page to learn extra about our Tacho merchandise or e-mail us at gross sales@orbcomm.com. Cody Lirette is Senior Content material Advertising and marketing Manager at ORBCOMM. With over seven years of marketing and communications experience for both the general public and non-public sector, he makes use of his ardour for progressive expertise and plain language to build compelling content material that gives value. Within the EU, rules on limiting commercial driver hours are thankfully in place and enforced by the DVSA to assist guarantee our roads are safer. Sadly, even with these rules in place it is proven that a big proportion of car accidents are all the way down to driver fatigue, the place such drivers are on the roads for long hours and their stage of alertness deteriorates.

Are all tachographs the identical? There are two various kinds of tachograph – digital and analogue. For all commercial vehicles first registered on, or after 1 May 2006, a digital tachograph has to be fitted. Recording info on an analogue tachograph involves a stylus cutting traces into a wax-coated chart, with three separate styluses marking velocity, distance travelled and driver’s exercise. Under particular circumstances this could also be longer however the circumstances would have to be such that an extension was deemed to be appropriate. The driver/operator or their consultant should full an software type D779B and submit it with the related price to the DVLA for replacement. Within the event of theft this should also be reported to the Police. In this booklet, we want to briefly hint the transformation that the tachograph has undergone over the last century to turn into the central compliance instrument in freight transport. I am, nevertheless, certain that journey is removed from over. At the Continental site in Villingen, we’ll proceed to shape the future of the tachograph with a ardour for precision and within the tradition of Kienzle Uhrenfabrik – hopefully for another a hundred years.